Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.

Author(s): Walsh SK, Hepburn CY, Kane KA, Wainwright CL

School of Pharmacy & Life Sciences, Institute for Health & Welfare Research, Robert Gordon University, Schoolhill, Aberdeen, UK. [email protected]

Subject: Heart Disease View the study

Abstract:

Cannabidiol (CBD) is a phytocannabinoid, with anti-apoptotic, anti-inflammatory and antioxidant effects and has recently been shown to exert a tissue sparing effect during chronic myocardial ischaemia and reperfusion (I/R). However, it is not known whether CBD is cardioprotective in the acute phase of I/R injury and the present studies tested this hypothesis.

Source: British Journal of Pharmacology
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