Cannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats.

Author(s): Parker LA, Mechoulam R, Schlievert C

Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario N2L 3C5, Canada

Subject: Nausea View the study


Rats display conditioned rejection reactions during an oral infusion of a flavor previously paired with an emetic drug; considerable evidence indicates that these rejection reactions reflect nausea. Here we report that cannabidiol, a major non-psychoactive cannabinoid found in marijuana and its synthetic dimethylheptyl homolog interfere with nausea elicited by lithium chloride and with conditioned nausea elicited by a flavor paired with lithium chloride.

Source: NeuroReport (Price: $49)
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