Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.

Author(s): Jones NA, Glyn SE, Akiyama S, Hill TD, Hill AJ, Weston SE, Burnett MD, Yamasaki Y, Stephens GJ, Whalley BJ, Williams CM

School of Pharmacy, University of Reading, Whiteknights, Reading RG6 6AJ, UK. [email protected]

Subject: Epilepsy View the study

Abstract:

Cannabis sativa has been associated with contradictory effects upon seizure states despite its medicinal use by numerous people with epilepsy. We have recently shown that the phytocannabinoid cannabidiol (CBD) reduces seizure severity and lethality in the well-established in vivo model of pentylenetetrazole-induced generalised seizures, suggesting that earlier, small-scale clinical trials examining CBD effects in people with epilepsy warrant renewed attention.

Source: European Journal of Epilepsy
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