Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus.

Author(s): Katsidoni V, Anagnostou I, Panagis G

Laboratory of Behavioral Neuroscience, Department of Psychology, School of Social Science, University of Crete, Rethymno, Crete, Greece

Subject: Addiction View the study


Cannabidiol is a non-psychotomimetic constituent of Cannabis sativa, which induces central effects in rodents. It has been shown that cannabidiol attenuates cue-induced reinstatement of heroin seeking. However, to the best of our knowledge, its effects on brain stimulation reward and the reward-facilitating effects of drugs of abuse have not yet been examined.

Source: Addiction Biology (Price: $38)
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