Cannabidiol Reduces Leukemic Cell Size – But Is It Important?

Author(s): Kalenderoglou N, Macpherson T, Wright KL

Division of Biomedical and Life Sciences, Faculty of Health and Medicine Lancaster University Lancaster, UK

Subject: Cancer View the study

Abstract:

The anti-cancer effect of the plant-derived cannabinoid, cannabidiol, has been widely demonstrated both in vivo and in vitro. However, this body of preclinical work has not been translated into clinical use. Key issues around this failure can be related to narrow dose effects, the cell model used and incomplete efficacy. A model of acute lymphoblastic disease, the Jurkat T cell line, has been used extensively to study the cannabinoid system in the immune system and cannabinoid-induced apoptosis...

Source: Frontiers in Pharmacology
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