Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence.

Author(s): Passie T, Emrich HM, Karst M, Brandt SD, Halpern JH

Hannover Medical School, Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover, Germany. [email protected]

Subject: PTSD View the study

Abstract:

It is known from clinical studies that some patients attempt to cope with the symptoms of post-traumatic stress disorder (PTSD) by using recreational drugs. This review presents a case report of a 19-year-old male patient with a spectrum of severe PTSD symptoms, such as intense flashbacks, panic attacks, and self-mutilation, who discovered that some of his major symptoms were dramatically reduced by smoking cannabis resin. The major part of this review is concerned with the clinical and preclinical neurobiological evidence in order to offer a potential explanation of these effects on symptom reduction in PTSD.

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