The cannabinoids as potential antiepileptics.

Author(s): Karler R, Turkanis SA

Subject: Epilepsy View the study


Comparative studies of the anticonvulsant properties of the cannabinoids and prototype antiepileptic drugs in numerous animal seizure models demonstrate that (1) as an anticonvulsant, cannabidiol (CBD), in contrast to delta 9-tetrahydrocannabinol (THC), is relatively selective in terms of both central nervous system (CNS), depressant and excitatory properties; (2) the potency of cannabidiol, unlike that of phenytoin and phenobarbital, varies greatly with the species...

Source: Journal of Clinical Pharmacology (Price: $38)
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