The effect of cannabidiol on ischemia/reperfusion-induced ventricular arrhythmias: the role of adenosine A1 receptors.

Author(s): Gonca E, Darıcı F

Biology Department, Faculty of Art and Sciences, Bülent Ecevit University, İncivez, Zonguldak, Turkey [email protected]

Subject: Heart Disease View the study

Abstract:

Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid with anti-inflammatory activity mediated by enhancing adenosine signaling. As the adenosine A1 receptor activation confers protection against ischemia/reperfusion (I/R)-induced ventricular arrhythmias, we hypothesized that CBD may have antiarrhythmic effect through the activation of adenosine A1 receptor.

Source: Journal of Cardiovascular Pharmacology and Therapeutics (Price: $40)
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