The endocannabinoid system and liver diseases.

Author(s): Caraceni P, Domenicali M, Bernardi M

Department of Internal Medicine, Cardioangiology, Hepatology, Alma Mater Studiorum University of Bologna, Bologna, Italy. [email protected]

Subject: Liver Disease View the study


Endogenous cannabinoids (EC) are ubiquitous lipid signalling molecules provided by a number of central and peripheral effects, which are mainly mediated by the specific cannabinoid receptors CB(1) and CB(2). Although the expression of these receptors is very low or even absent in the healthy liver, a considerable series of experimental studies and some clinical observations have recognised the EC system as an important player in the pathophysiology of liver diseases.

Source: Journal of Neuroendocrinology
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