The influence of biomechanical properties and cannabinoids on tumor invasion.

Author(s): Hohmann T, Grabiec U, Ghadban C, Feese K, Dehghani F

Department of Anatomy and Cell Biology , Martin Luther University Halle-Wittenberg , Halle (Saale) , Germany

Subject: Cancer View the study

Abstract:

Cannabinoids are known to have an anti-tumorous effect, but the underlying mechanisms are only sparsely understood. Mechanical characteristics of tumor cells represent a promising marker to distinguish between tumor cells and the healthy tissue. We tested the hypothesis whether cannabinoids influence the tumor cell specific mechanical and migratory properties and if these factors are a prognostic marker for the invasiveness of tumor cells.

Source: Cell Adhesion & Migration
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